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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66beb4893b4cec6d24741ac0a82a26b789a0a055cef89cc95a6e9a768d19fe7b' 
  AND token = 'eJSuwzX0vcf/Ps9VdxHdeyVXzLWvsf9EiV83hf4sNOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}