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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454fdc19b2a88c6565a77582e98a73c880451435188dda02b057616e7a88b618' 
  AND token = 'CpxXVLCZ2wCSqF0N6LT9EHzi7gIGKQI6eUSAFgLxt5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}