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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f3dec2b0d8ebe1bd8861e23aebeabea77cc67ec869655adb5b0f0fb50a316f' 
  AND token = 'aPtMyQumLDlTCb+9E7PLY9/1md4TygMMAmm7bf/O2SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}