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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc241b69f6af31c90c71200af93cb7c195f7c8f740951a3597dfe3df1fd141b' 
  AND token = 'c90z+KIlFrCHT5mxT1VWYtDGgTUcK+yNoV/SPeTPpLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}