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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a181239eb509e59834a7464b722d96057b90bc4cbfac07b2bd1e476cd5c6805' 
  AND token = 'zvGnkgD40sbl4B4fXCu9RW9bNcxc69PAL/JYD0SNBtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}