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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22bcde42bbd6b69d9865983cba410588748addce371ae7831662d807c501ff07' 
  AND token = '7W9vtv/+eGd+k1sjqGFCKSEp1fToq2olwUYdDom8Nl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}