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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389c8585af6c42d27756924e1fc7144316f552b04756a78e6aa6fe58a04e6904' 
  AND token = 'whaFy/WabvLv92RgouOM1C8TnCr7Zbo0D4Ztb0rIxYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}