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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def0b16aae4dba2cdc717722ccd94deeae193e91cedbcd883bb037ba4dbe29bf' 
  AND token = 'f4gifrk/vuFm0pkZY5t2/kwRiJbzRKQlBi++iYy67MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}