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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11b3f05387e6c294e7f0fe7c5e761f63b70799e6bd949a0f22080367cce0c895' 
  AND token = '7DWk/mm0nreglhOHMpBRswCThHJumkVwEypIF6EadCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}