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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03de1d850bfc5e296f3e21237b3fd78601a9a445a0fff17d9065b05dbc32bc8e' 
  AND token = 'hA1ndmqAJ12oWNr7NmYgZy8lnsbk7V6bnu6ktzZv7Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}