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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14fa93c4db35667227244e0f8f91300e3fd50d9d42be33a8fb41d69c2f6e64a' 
  AND token = 'Z4JNRE1vxH1efCiw1CYjJQyucwKN+RExTgvOY8PL3P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}