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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16583626f9a936899b47ecb1b52e518af6ef2b6d418d04d62aa881d5971da00' 
  AND token = '2bTEg38y7CL7NRhcF2EDOjlFPR6tsqVazb4WPLNrjRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}