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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8330165ac3af19cf166e9eb0a3c43fa6fe3ae9b50e77f48dd3d2fdc6f1867a91' 
  AND token = '1PHY0OxmBU+ahIVcvFlhaO8PRKcsV4PwU+7Qk2Da5AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}