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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac050e0a1e5ffc544084ee6fb624b2c04d20ceee595b224137e152d3fd624638' 
  AND token = 'd7UVniVw5LH5BTLLReVTp3Hrlbb4Pcn7CQHJmWNJFvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}