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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666bcc7f86b28a12462ff7211d09bdd7cd7a9aa4f3dd0165f60284def5d99980' 
  AND token = '1Bz3EjBHgnTjIRpMkMklnnDQOf4NAVTo6MuODJYsQIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}