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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3d3d7508cae186d609a2568349352fff4c527388e4ad323ebb0158f746ef5c' 
  AND token = 'HzpV1ja70Ram0+Dza3B1UVitWsuGLDbfuyZdY7OV27c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}