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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37780222e0801db3520fd4d7a8c2cc096ee0d2b85c39a5dce9bfadbc7810d3bf' 
  AND token = '0GaMfr0rJXfAuAYwZ4f+K/phWSNq9JwxGx3mrRs6oM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}