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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3e9e99d71804678eb9d32c2922ba330ae8d35c672a29a636b8bf7ba182f9500' 
  AND token = 'G2Z9vOTAl/I2oT0r/g5XzH+jchKrEsFTPZDLP4lactk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}