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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75583faea7f25bad52d19e981786b7393f95ac8a16e14ccfba1d54b163e8a72a' 
  AND token = 'HeA8pyfESb4WVuGLpB/GwYecD74HjJJirr+Lg9cWDSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}