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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a23227ed57c43f737e8766218ff21bd4795c68ba52a21d74dcf71caa082f5970' 
  AND token = 'IyEA0Y9/p1RT09cx7VMyAx0tJznFWnLfCFlu5bO4+3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}