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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e072bc58c68f653d9cec4ea69613619fd69be955eba4464e6ff2ffed8f071c7' 
  AND token = 'SV/L+3kctDdq04OAX4e/h8Dk2axUJD1Ywnr0aDTJkR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}