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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43244027ac70b062decb8ee74b74d21cb8f825b7581f4929ec6cf7fefb33440' 
  AND token = 'Kjpc+xFiSbSUf73SJtEfVOk94tLNDCsizcEihMBzDPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}