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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291c044604061db15b738d628fba3f769a994b135eefecd2abababcd91de32c6' 
  AND token = 'fwimA5aD8ASUgHlJ2fCZ14JCm7+FZlKnCU8ZmqZgS9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}