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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd482ee716f269b7fd4e6a06a7350d4db4461f6afd8fcc3472a222bab74a7d7ff' 
  AND token = 'Kk1pdW7kYnOHmx8hMbZUXL9s08qg7qoCvzDDbkRIvSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}