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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae1d1f339b95bf07d940165673386338ec2fb01f749571fd816c50302824e86' 
  AND token = '1WvyCF1SPhA6F1a+24nmseyu50iIYhcRYBDJ234I3is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}