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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '820fa37d67539e9b74f24c0490c7c08220260c6cea0734859a5cb363e52a03d3' 
  AND token = '0Ctdwq22Gd2haUhL2qMDlgkIGO9HrFO5xYYEI4hu3rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}