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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0c88499733e0c4e5387746c5b74103144ac6aae31a8298d011b0b1ad82ba5c' 
  AND token = 'nVx9wrHvTU8wj3WHwMHybaONJZ2guOh94N1sLKdVkso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}