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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b127ea92d5a4b25727748918d4ce1be2e95415af513be2d23ed1b3bcbdb4d6' 
  AND token = 'wXISUueULEDykX/o3kISXCRT18M1LrJ2c5EI/TBxLCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}