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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '551296635ea9c9f25452953cdf39704f44ca4a421834b0f04872941787faa422' 
  AND token = 'u3pXlfLxmKFZ4nOodPQCNs8HK4fa2yZ44uXCG8B/gI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}