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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39c91fd79f83ab4a455e698dbdf1defcd2780b8de67b1c595f3f09391bb15c6b' 
  AND token = 'lTL/XQI/EZUqvOEs2f+5VV25XUejFip4IeXOvruk2C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}