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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880af7ee76ca890ed386d928e04db9c7f00ffe6c104d67efc4766a7aac7cd769' 
  AND token = 'oU8+mEKafuRHj0BNUDYB6Jx5mJA9NYOcwEXxBy7KvSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}