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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e15194b35e9978decbff1fd40972ef512e69b2029723c37db499cf8e47532c6' 
  AND token = 'QdF/Avc4wrMewq7OmARwYA9UDe6hzCAzpze85Tgfvyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}