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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2d1149f29b59fda975e058e24506626a6eff00925bca1e8b08ec920782de40' 
  AND token = '5x1E4Dt7YQ5us3ij4pvohDfc9hxZcwB6I4VkAL4Dp4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}