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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5222218b92eab0ed6c1aca60565b559c8d314416b0720b822c01d00d51f5a70' 
  AND token = 'Prep/IUjMIQW/zWscoEel4TmKI9KXgkT3ZcOV49qKM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}