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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725d5eb291dfc8732aec308964ccdaea4fbe4af0a2b0d12a00ea2d93ed9243bd' 
  AND token = 'l0uhJuwS/OWSgaKFpAoLjEjkYJ5PRGQhOiDgzO+mb14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}