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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f21c5bd688f25bd6be8062867390c5200032a32c15aefb6e9cbe95ae9a50488' 
  AND token = 'n7eJ6GhlirDPn573t978eiA31/HzNBP+s0QMrfyoTFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}