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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e531e52af60e0b3735ccde93382039a4f9fa2e7097738718e7ff60dc4edabc' 
  AND token = 'F7z2Wk2jRr6HI4mvNa5/4Ior5/UE30zrGXd1b4AsbyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}