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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0593ebd08e6a4513adb65e30c25415d24f4b282620e7d75590dd3ef0b7ee9b' 
  AND token = '19v0a2YGh6Z2rOGIpvauKTwmTRuFZ0hnfC2QIVfC3+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}