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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b204647947f65b26accf7d3051fbbc7da7a04cd6aa29f23c4fbe382fd25cc5' 
  AND token = 'f6jd8JibdgRFW+apm960SmKpUN7vW4BgWsj7kS/skTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}