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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1f70afef6d380f2e3a5566de59f003d63b7d9b2e23dc886866ad1e995d0f909' 
  AND token = 'CoEFh6wwbyp2rBgrbLt41eI1/urW8sw30HlAvkCOpBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}