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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf1d1670ddd87733900deff809ebc9241a361b74521ff4a3450a080d2b525b0' 
  AND token = 'EA0osQuYVlr9H49cTXoXT85JjCRq39fgFXtMYmfOmSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}