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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb8bfb394703c0db8fb2998001e9f3810c0e86d2198286270d62d8da15ea3bf5' 
  AND token = 'NEXn2DtP68V9b0CoEz3UtpNARpVEbEj1XhXvZVfKaBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}