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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b660f29cb744c364226c709b70db09e38d6c8c88c6bd86ad6bc5c9cc3be04b43' 
  AND token = 'dv9F8hcB75lcGqBTgrjnbPKYBO56nxBs9Xxn2Fi/0cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}