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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcc4f464220c8209698f67bb43da38a6780620c7445d5c1e3a259ea4b3f316c3' 
  AND token = '0pK0l346X7OO+d/UpCQzpKyPF3o6j3+2lozyOZm8AZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}