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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780fd56ad96e93742775a8463992c57413cff2ac5b8433ea27766181bb572c9f' 
  AND token = 'r886eH82Jb/5oJarPsWNYz/0UiJQRA7KKbf6a3FOUI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}