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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b6b1c8d7413a9fed1a26465db235aaa1f2119d4c59cf5b57ab0123d0f88cfe' 
  AND token = '4bZ/47V6EKp/R11YDRYUYeD++B7HN3cf6BOlsz/N7iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}