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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5a0ddc95e2113bfce35924f8c6f2ca42349c406dae852c985bad0c7e2187e3' 
  AND token = 'VzCMY9vNgS/e+7yTLobWX18W36Xq8VpQpo5p/Iahrsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}