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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c0346d00f36680f3401ad3496d2fae08459999554d35834edeb95de7d11118' 
  AND token = '3E5KMm8uYXfDpnOpj+KBG5a3w1ibPPFUBr9FygohtdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}