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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2303288804c3fd4fe29550b5e542a7d7b90a81791122fda469efe03bc2c8c17' 
  AND token = 'GGrhI1lJ8iv0r8y9CTNuqlvGv6M9j3z5FweFmSRBU4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}