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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02269a43052006411de6f466f6bb153eee02b1ee790b93009b9da74bc9e1d8ca' 
  AND token = '3lV7/Qh24BvLVE6Ysf6kuh04qBBRmuuUDny0V8rlc6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}